Thi-DPPY

SKU: orb1686032

Description

Thi-DPPY is a potent and orally active dual inhibitor of JAK3 (IC50: 1.38 nM) and BTK (IC50: 62.4 nM). It demonstrates anti-proliferative effects in HBE cells in vitro and exhibits anti-inflammatory activity in vivo, showing research potential for idiopathic pulmonary fibrosis (IPF) and related inflammatory disease models.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2307699-34-7
• MW: 566.07
• Formula: C₂₈H₂₈ClN₅O₄S
• SMILES: O(C1=C2C(=NC(NC3=CC(Cl)=C(OCCCN4CCOCC4)C=C3)=N1)C=CS2)C5=CC(NC(C=C)=O)=CC=C5
• Target: Others,JAK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156014173