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Thalifendine chloride

SKU: orb1981802

Description

Thalifendine chloride is a demethylated metabolite of berberine, formed by CYP51 at the C-10 position. It exhibits cytotoxic activity against P-388 murine leukemia cells (ED50=0.84 µM) and shows weak antiplasmodial activity against Plasmodium falciparum in vitro.

Research Area

Infectious Disease & Virology, Metabolism Research

Images & Validation

Key Properties

CAS Number4668-19-3
MW357.79
FormulaC19H16ClNO4
SMILESO(C)C1=C2C=[N+]3C(C=4C(=CC5=C(C4)OCO5)CC3)=CC2=CC=C1O.[Cl-]
TargetParasite,Drug Metabolite

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Thalifendine chloride (orb1981802)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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