Thalidomide-O-PEG1-OH

SKU: orb3028532

Description

Thalidomide-O-PEG1-OH is a PROTAC linker characterized by its combination of Thalidomide with O-ethyl. Thalidomide acts as a ligand for the E3 ubiquitin ligase, leading to protein ubiquitination and subsequent proteasomal degradation. Additionally, the hydroxy group serves as a versatile handle, facilitating the formation of more complex structures through various reactions.

Research Area

Pharmacology & Drug Discovery, Pharmacology & Drug Discovery; Cell Biology

Key Properties

• CAS Number: 2416234-31-4
• MW: 318.281
• Formula: C₁₅H₁₄N₂O₆
• SMILES: O=C1NC(=O)C(N2C(=O)C=3C=CC=C(OCCO)C3C2=O)CC1
• Target: PROTAC Linker

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PROTAC Linker