Thalidomide-O-C6-NH2 TFA

SKU: orb1909204

Description

This compound is a key component of the PROTAC molecule dTAG-13, serving as the E3 ligase ligand-linker conjugate. It enables the targeted degradation of FKBP12F36V and BET proteins, a strategy widely used in chemical biology and oncology research for target validation and mechanistic studies both in vitro and in vivo.

Research Area

Cell Biology, Immunology & Inflammation; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1957235-99-2
• MW: 487.43
• Formula: C₂₁H₂₄F₃N₃O₇
• SMILES: O=C(O)C(F)(F)F.O=C1NC(=O)C(N2C(=O)C=3C=CC=C(OCCCCCCN)C3C2=O)CC1
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

134495955