Thalidomide-O-C6-NH2 hydrochloride

SKU: orb1303320

Description

This compound is a synthesized PROTAC linker-conjugate incorporating a thalidomide-based E3 ligase ligand. It is widely used in chemical biology and drug discovery research for constructing proteolysis-targeting chimeras (PROTACs) to study targeted protein degradation in vitro and in vivo.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2245697-88-3
• MW: 409.864
• Purity: 97.45% (May vary between batches)
• Formula: C₁₉H₂₄ClN₃O₅
• SMILES: O=C1N(C2CCC(NC2=O)=O)C(C3=CC=CC(OCCCCCCN)=C31)=O.[H]Cl
• Target: Autophagy,E3 Ligase Ligand-Linker Conjugates,Apoptosis
• Solubility: 10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (8.05 mM);H2O:25 mg/mL (61 mM);DMSO:83.33 mg/mL (203.31 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

dTAG-13, E3 Ligase Ligand-Linker Conjugates, E3 Ligase LigandLinker Conjugate, E3 Ligase Ligand-Linker Conjugate, BET, 4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride, FKBP12(F36V), E3LigaseLigandLinkerConjugate, Inhibitor, inhibit, Thalidomide O C6 NH2 hydrochloride, ThalidomideOC6NH2 hydrochloride, Thalidomide-O-C-6-NH2 hydrochloride, Thalidomide-O-C6-NH2 Hydrochloride

Compound Identifiers

PubChem CID

134812847