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Thalidomide-NH-C4-NH2 TFA
Catalog Number: orb1987630
| Catalog Number | orb1987630 |
|---|---|
| Category | Small Molecules |
| Description | Thalidomide-NH-C4-NH2 TFA (compound 29c) is a conjugate composed of an E3 ligase ligand-linker that integrates a Thalidomide-based cereblon ligand and a linker moiety. This compound is used as a component in PROTAC BRD2/BRD4 degrader-1, a highly potent and selective degrader targeting BET proteins BRD4 and BRD2[1]. |
| CAS Number | 2093387-50-7 |
| Purity | 98.00% |
| MW | 458.39 |
| SMILES | O=C(O)C(F)(F)F.O=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCCCCN)C3C2=O)CC1 |
| Formula | C19H21F3N4O6 |
| Biological Activity | Thalidomide-NH-C4-NH2 TFA (compound 29c) is a conjugate consisting of an E3 ligase ligand-linker, incorporating the Thalidomide-based cereblon ligand and a linker moiety. This compound, Thalidomide-NH-C4-NH2 TFA, is utilized as a component in PROTAC BRD2/BRD4 degrader-1, which is a highly potent and selective degrader targeting BET proteins BRD4 and BRD2[1]. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
