Thalidomide-NH-C4-Boc

SKU: orb2944941

Description

Thalidomide-NH-C4-Boc is a Cereblon (CRBN) E3 ligase ligand-linker conjugate used in constructing PROTAC molecules, such as degrader-1 targeting CARM1 and IKZF3. This compound is a key chemical tool for developing heterobifunctional degraders in oncology and epigenetic research, applicable in both in vitro and in vivo experimental settings.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2226139-38-2
• MW: 443.493
• Formula: C₂₃H₂₉N₃O₆
• SMILES: O=C(OC(C)(C)C)CCCCCNC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
• Target: E3 Ligase Ligand-Linker Conjugates

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

146410803