Thalidomide-4-piperidineacetaldehyde

SKU: orb2945626

Description

Thalidomide-4-piperidineacetaldehyde is a bifunctional linker conjugate incorporating a cereblon (CRBN) E3 ligase ligand. It serves as a key intermediate in constructing PROTAC molecules, such as H122, for targeted protein degradation research in biochemical and cellular assays.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2222115-36-6
• MW: 383.398
• Formula: C₂₀H₂₁N₃O₅
• SMILES: O=CCC1CCN(C2=CC=C3C(=O)N(C(=O)C3=C2)C4C(=O)NC(=O)CC4)CC1
• Target: E3 Ligase Ligand-Linker Conjugates

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

134413898