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Thalidomide 4-fluoride

SKU: orb1299536

Description

Thalidomide 4-fluoride is a Cereblon (CRBN)-directed E3 ligase ligand used to construct PROTAC molecules, such as PROTAC IRAK4 degrader-1. This compound enables targeted protein degradation, facilitating the study of IRAK4 signaling pathways in both cellular and biochemical research contexts.

Research Area

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number835616-60-9
MW276.22
Purity99.12% (May vary between batches)
FormulaC13H9FN2O4
SMILESO=C1N(C(=O)C=2C1=CC=CC2F)C3C(=O)NC(=O)CC3
TargetApoptosis,Autophagy,IRAK,Ligands for E3 Ligase
SolubilityDMSO:199 mg/mL (720.44 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, IRAK4, Ligand for E3 Ligase, LigandforE3Ligase, Ligands for E3 Ligase, Inhibitor, Cereblon ligand4, Cereblon ligand 4, Cereblon ligand-4, E3 ligase Ligand 4, E3 ligase-recruiting Moiety, Thalidomide 4fluoride, Thalidomide 4-fluoride, Thalidomide, Thalidomide 4 fluoride

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Key Properties

No computed properties available.

Protocol Information

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500 mg
$ 70.00
DispatchUsually dispatched within 3-5 working days
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