THAL-SNS-032

SKU: orb1307672

Description

THAL-SNS-032 is a proteolysis-targeting chimera (PROTAC) designed to selectively degrade CDK9. This small molecule is a research tool for investigating CDK9-dependent transcription in oncology and virology, with utility in both cellular and in vivo models for studying transcriptional regulation and disease mechanisms.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2139287-33-3
• MW: 869.02
• Purity: 99.68% (May vary between batches)
• Formula: C₄₀H₅₂N₈O₁₀S₂
• SMILES: O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCOCCOCCOCCNC(CN4CCC(C(NC=5SC(SCC=6OC(C(C)(C)C)=CN6)=CN5)=O)CC4)=O
• Target: CDK,PROTACs
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (3.8 mM);DMSO:97 mg/mL (111.62 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CDK9, CDK, Cyclin dependent kinase, Inhibitor, inhibit, THAL SNS 032, THAL-SNS 032, THALSNS032, THAL-SNS032, THAL-SNS-032, PROTACs

Compound Identifiers

PubChem CID

131801483