TH7127

SKU: orb2567319

Description

TH7127 is a selective SAMHD1 inhibitor that blocks its enzymatic hydrolysis of nucleotide analogs such as ara-CTP and Cl-F-ara-ATP. This small molecule is a valuable research tool for investigating SAMHD1's role in nucleotide metabolism and resistance mechanisms in cancer and virology, applicable in both cellular and biochemical assays.

Key Properties

• MW: 345.4
• Purity: 99.89% (May vary between batches)
• Formula: C₂₀H₁₉N₅O
• SMILES: COc1ccccc1-c1cn2ccnc2c(NCCc2ccccn2)n1
• Target: Others
• Solubility: DMSO:100 mg/mL (289.52 mM);H2O:< 1 mg/mL (insoluble)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

TH7 127, TH7127, TH7-127, SAMHD1

Compound Identifiers

PubChem CID

172009917