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TH-Z835

SKU: orb1944484

Description

TH-Z835 is a mutant-selective KRAS(G12D) inhibitor with an IC50 of 1.6 μM.This compound inhibits mantGMPPNP/GPPNP exchange and GPPNP/mantGMPPNP exchange.

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Key Properties

CAS Number2766209-50-9
MW498.66
FormulaC30H38N6O
SMILESO(C[C@H]1N(C)CCC1)C2=NC(=C3C(CN(CC3)C=4C5=C(C=CC4)C=CC=C5C)=N2)N6CC7NC(C6)CC7
TargetRas,Apoptosis

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Protocol Information

TH-Z835 (orb1944484)

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