TH-Z816

SKU: orb2565164

Description

TH-Z816 is a reversible KRAS(G12D) inhibitor with an IC50 of 14 µM. It is a research tool for studying oncogenic KRAS signaling and has been utilized in both in vitro cellular assays and in vivo xenograft models relevant to pancreatic and colorectal cancers.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2847881-42-7
• MW: 486.65
• Formula: C₂₉H₃₈N₆O
• SMILES: C[C@H]1N(C2=C3C(CN(CC3)C=4C5=C(C=CC4)C=CC=C5C)=NC(OC[C@H]6N(C)CCC6)=N2)CCNC1
• Target: Kras,Ras

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162371030