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TGN-020

SKU: orb1302089

Description

TGN-020 is a small molecule inhibitor of Aquaporin 4 (AQP4; IC50 = 3.1 µM), the predominant water channel in the central nervous system. It is a valuable research tool for studying water homeostasis, neuroinflammation, and edema in models of stroke, traumatic brain injury, and neuromyelitis optica spectrum disorders (NMOSD) in both in vitro and in vivo settings.

Research Area

Neuroscience

Images & Validation

Key Properties

CAS Number51987-99-6
MW206.22
Purity>98%
FormulaC8H6N4OS
SMILESO=C(Nc1nncs1)c1cccnc1
TargetAquaporin
SolubilitySoluble in DMSO (up to 10 mg/ml with warming)

Bioactivity

Target IC50
AQP4:3.1 μM

Storage & Handling

StorageRT
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

edema, AQP4, Aquaporin 4, Inhibitor, glial, inhibit, PROTAC Linker, PROTACLinker, PROTAC Linkers, TGN 020, TGN020, TGN-020, scar

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  • TGN020 [orb1221188]

    >98% (HPLC)

    51987-99-6

    206.22

    C8H6N4OS

    5 mg, 10 mg, 25 mg, 100 mg, 50 mg, 1 g, 500 mg, 200 mg
Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

TGN-020 (orb1302089)

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10 mg
$ 210.00
50 mg
$ 480.00
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