TGFβR-IN-1

SKU: orb1983162

Description

TGFβR-IN-1 is a tumor-activated prodrug that provides sustained release of a TGFβ receptor inhibitor. This long-acting proagent is designed for research into TGFβ signaling in oncology, enabling both in vitro mechanistic studies and in vivo evaluation of antitumor efficacy in preclinical models.

Research Area

Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2857845-36-2
• MW: 1791.41
• Formula: C₈₄H₁₂₁ClFN₁₇O₂₃
• SMILES: CC(C)C[C@H](NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@H](NC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCC(O)=O)C(O)=O)C(O)=O)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)Nc1ccc(COC(=O)NCOCCn2cnc(c2-c2ccc3ncc(C#N)n3n2)-c2ccc(F)c(Cl)c2)cc1
• Target: TGF-beta/Smad,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162366974