TGFBR1-IN-1

SKU: orb1708373

Description

TGFBR1-IN-1 is a potent and selective small molecule inhibitor of ALK5 (TGFβRI), exhibiting an IC50 in the 10-100 nM range. This compound is a valuable research tool for investigating TGF-β signaling in fibrosis, cancer, and other disease models, applicable in both cellular and biochemical assays.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2170830-26-7
• MW: 427.48
• Formula: C₂₃H₁₇N₅O₂S
• SMILES: C(NC1=CC=C(O)C=C1)(=O)C=2C=C(N(N2)C=3N=C(C)C=CC3)C=4C=C5C(=CC4)N=CS5
• Target: ALK,TGF-beta/Smad

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

138747570