TGF-8027

SKU: orb3173784

Description

TGF-8027 is a selective 5-HT2A receptor agonist capable of crossing the blood-brain barrier. It exhibits EC50 values of 3.3 nM for 5-HT2A, 160 nM for 5-HT2C, and 7600 nM for 5-HT2B receptors. In mice, TGF-8027 has an EC50 of 14 nM for 5-HT2A and 210 nM for 5-HT2C receptors. It can induce head-twitch responses in mice and is useful for researching diseases targeting the 5-HT2A receptor, such as depression.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• Target: 5-HT Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

5-HT Receptor