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| Catalog Number | orb2564675 |
|---|---|
| Category | Small Molecules |
| Description | TF-S14 is an inverse agonist of RORγt. It functions by binding to RORγt and inhibiting its activity, leading to a reduction in Th17 cell-associated cytokine production, including IL-17A, IL-21, and IL-22. TF-S14 is applicable in research related to autoimmune diseases and allogeneic transplant rejection. |
| Target | ROR |
| MW | 397.53 |
| CAS Number | 2425563-60-4 |
| Formula | C22H27N3O2S |
| SMILES | C(=O)(C=1C2=C(SC1NC(=O)C=3C=CC=NC3)CCCC2)N4[C@H](C)C[C@H](C)CC4 |
| Storage | -20°C |
| Research Area | Metabolism Research |
| Note | For research use only |
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