Tetrahydrozoline hydrochloride

SKU: orb1300540

Description

Tetrahydrozoline hydrochloride, an imidazoline-based alpha-adrenergic receptor agonist, is utilized in ophthalmic research as a vasoconstrictor. It serves as a valuable tool for studying adrenergic signaling pathways in both in vitro receptor binding assays and in vivo models of ocular redness and hypertension.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 522-48-5
• MW: 236.74
• Purity: 99.97%
• Formula: C₁₃H₁₆N₂·HCl
• SMILES: Cl.C1CN=C(N1)C1CCCC2=CC=CC=C12
• Target: Adrenergic Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (4.22 mM);H2O:43 mg/mL (181.63 mM);Ethanol:25 mg/mL (105.6 mM);DMSO:10 mg/mL (42.24 mM)

Bioactivity

• In Vivo:
  Tetrahydrozoline HCl inhibits settlement of the Barnacle Balanus improvisus at 1 μM.
• In Vitro:
  Tetrahydrozoline HCl is an imidazoline derivative with alpha receptor agonist activity. Its main mechanism of action is the constriction of conjunctival blood vessels.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Tetrahydrozoline, Tetrahydrozoline HCl, Tetrahydrozoline hydrochloride, Tetrahydrozoline Hydrochloride, Tetryzoline, Tetryzoline Hydrochloride, Tetryzoline hydrochloride, Tyzine, α-adrenergic receptor, Murine Plus, inhibit, ophthalmic, nasal, Inhibitor, conjunctival, congestion, Beta Receptor, Adrenergic Receptor, AdrenergicReceptor

Compound Identifiers

PubChem CID

10648