Tetrahydrocoptisine

SKU: orb1302288

Description

Tetrahydrocoptisine (Stylopine) is a bioactive small molecule with demonstrated anti-inflammatory properties. It exerts protective effects in models of acute lung injury and gastric damage by suppressing NF-κB signaling, pro-inflammatory cytokines (TNF-α, IL-6), and MAPK pathways, as shown in both in vitro and in vivo research.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Signal Transduction

Key Properties

• CAS Number: 4312-32-7
• MW: 323.34
• Purity: 99.96% (May vary between batches)
• Formula: C₁₉H₁₇NO₄
• SMILES: C1Oc2cc3CCN4Cc5c6OCOc6ccc5CC4c3cc2O1
• Target: Interleukin,PERK,NO Synthase,Parasite,ERK,p38 MAPK,NF-κB
• Solubility: Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble;DMSO:4.17 mg/mL (12.9 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NFkB, NF-kB, NFκB, NF-κB, ERK, STYLOPINE, p38MAPK, p38 MAPK, Tetrahydrocoptisine

Compound Identifiers

PubChem CID

6770