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Tesmilifene fumarate

SKU: orb1305825

Description

Tesmilifene fumarate, also known as DPPE fumarate, is a selective H1C receptor antagonist. It has been utilized in research to study receptor function and has shown potential in experimental models for investigating conditions like cancer and cognitive disorders.

Research Area

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1185241-83-1
MW399.48
Purity99.86%
FormulaC23H29NO5
SMILESOC(=O)\C=C\C(O)=O.CCN(CC)CCOc1ccc(Cc2ccccc2)cc1
TargetHistamine Receptor
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.52 mM);DMSO:248 mg/mL (620.81 mM)

Bioactivity

In Vivo
Tesmilifene (DPPE, 20 mg/kg (s.c.) and 20 μg (icv in 5 μL)) potentiated seizures induced by both convulsants.
In Vitro
Tesmilifene may indirectly modulate the effects of 12(S)-HETE in cancer cells, influencing the susceptibility of cellular DNA to chemotherapy.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Inhibitor, Histamine Receptor, HistamineReceptor, inhibit, chemotherapy, DPPE, DPPE Fumarate, DPPE fumarate, anti-histaminic, seizure, Tesmilifene, Tesmilifene Fumarate, Tesmilifene fumarate

Similar Products

  • Tesmilifene fumarate [orb1219059]

    >98% (HPLC)

    1185241-83-1

    399.48

    C23H29NO5

    100 mg, 200 mg, 2 mg, 5 mg, 10 mg, 25 mg, 1 g, 500 mg, 50 mg
Quality Guarantee

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Key Properties

No computed properties available.

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Tesmilifene fumarate (orb1305825)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

5 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 90.00
10 mg
$ 100.00
25 mg
$ 160.00
50 mg
$ 220.00
100 mg
$ 310.00
200 mg
$ 430.00
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