Tesevatinib tosylate

SKU: orb2802105

Description

Tesevatinib tosylate (XL-647 tosylate) is an orally bioavailable, brain-penetrant multi-kinase inhibitor targeting EGFR, HER2, VEGFR2, and Src. It demonstrates potent antitumor activity in glioblastoma models in vitro and has shown efficacy in preclinical in vivo studies for cancers including NSCLC and glioblastoma.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 1000599-06-3
• MW: 663.59
• Formula: C₃₁H₃₃Cl₂FN₄O₅S
• SMILES: S(=O)(=O)(O)C1=CC=C(C)C=C1.N(C=1C2=C(C=C(OC[C@@H]3C[C@]4([C@@](C3)(CN(C)C4)[H])[H])C(OC)=C2)N=CN1)C5=C(F)C(Cl)=C(Cl)C=C5
• Target: VEGFR,Src,EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

71301378