Teriflunomide impurity 3

SKU: orb1219192

Description

Teriflunomide impurity 3 is a selective COX-1 inhibitor(IC50 of 30 μM). It is less active against COX-2 (IC50>100 μM).

Key Properties

• CAS Number: 1011244-72-6
• MW: 280.25
• Purity: >98% (HPLC)
• Formula: C₁₄H₁₁F₃N₂O
• SMILES: O=C(NC1=CC=C(C(F)(F)F)C=C1)C2=CC=C(N)C=C2
• Target: COX
• Solubility: DMSO:250 mg/mL (892.06 mM; Need ultrasonic)

Bioactivity

• In Vitro:
  Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide; compound 11q) is an amide-bond-reversed compound bearing trifluoromethyl and amino substituents showed potent COX-1-selective inhibitory activity.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

4-Amino-N-(4-trifluoromethylphenyl)benzamide

Quick Database Links

Gene Symbol

COX