Terbufibrol

SKU: orb1707802

Description

Terbufibrol is a research compound that effectively lowers serum total cholesterol in both normocholesterolemic and hypercholesterolemic male rats. It serves as a useful tool for in vivo pharmacological studies investigating lipid metabolism and potential therapeutic approaches for dyslipidemia.

Key Properties

• CAS Number: 56488-59-6
• MW: 344.4
• Purity: 98.86% (May vary between batches)
• Formula: C₂₀H₂₄O₅
• SMILES: O(CC(COC1=CC=C(C(O)=O)C=C1)O)C2=CC=C(C(C)(C)C)C=C2
• Target: Others
• Solubility: DMSO:3.45 mg/mL (10.02 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.9 mM)

Bioactivity

• In Vivo:
  Terbufibrol (20-200 mg/kg) reduces serum TC in animals on all three diets, with cholesterol reduction percentages of 154%, 80%, and 70% for cholesterol, high protein, and fat diets, respectively. It also lowers HDL, HDL-TC, LDL, LDL-TC, and LDL-TC/PL in animals fed an HPF-diet, with LDL-TC reduction being dose-dependent. Clofibrate (200 mg/kg) lowers HDL and HDL-TC while increasing LDL.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Terbufibrol

Compound Identifiers

PubChem CID

41907