Terazosin hydrochloride

SKU: orb1224412

Description

Terazosin is a selective alpha1-antagonist used for treatment of symptoms of benign prostatic hyperplasia (BPH). It also acts to lower blood pressure, so it is a drug of choice for men with hypertension and prostate enlargement. It works by blocking the action of adrenaline on smooth muscle of the bladder and the blood vessel walls.(In Vitro):Terazosin does not discriminate cloned α1-adrenoceptor subtypes transiently expressed in COS cells.(In Vivo):Terazosin can be used to promote stone discharge in treatment of ureteral stones. Terazosin is reportedly safe and effective in treatment of distal ureteral stones, especially stones >5 mm.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 63074-08-8
• MW: 423.89
• Purity: >98% (HPLC)
• Formula: C₁₉H₂₆ClN₅O₄
• SMILES: O=C(N1CCN(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)CC1)C4OCCC4.[H]Cl
• Target: Adrenergic Receptor
• Solubility: Water: 50 mM

Bioactivity

• In Vivo:
  Terazosin can be used to promote stone discharge in treatment of ureteral stones. Terazosin is reportedly safe and effective in treatment of distal ureteral stones, especially stones >5 mm.
• In Vitro:
  Terazosin does not discriminate cloned α1-adrenoceptor subtypes transiently expressed in COS cells.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Terazocin HCl | Vasocard | Hyprin | A-45975 | A 45975 | A45975

Quick Database Links

Gene Symbol

Adrenergic Receptor