Teneligliptin hydrobromide

SKU: orb1300273

Description

Teneligliptin hydrobromide is a potent and long-acting DPP-4 inhibitor, demonstrating competitive inhibition with IC50 values around 1 nM in various in vitro assays. This research compound is widely used in studies of type 2 diabetes, enabling investigations into glucose metabolism and insulin secretion in both cellular and animal models.

Research Area

Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 906093-29-6
• MW: 628.86
• Purity: >99.99% (May vary between batches)
• Formula: C₂₂H₃₀N₆OS·5/2BrH
• SMILES: Br.Br.Br.Br.Br.Cc1cc(N2CCN(CC2)C2CNC(C2)C(=O)N2CCSC2)n(n1)-c1ccccc1.Cc1cc(N2CCN(CC2)C2CNC(C2)C(=O)N2CCSC2)n(n1)-c1ccccc1
• Target: JNK,Interleukin,DPP-4,Immunology/Inflammation related,ROS,Proteasome,AMPK,NOD-like Receptor (NLR),p38 MAPK,NF-κB,Apoptosis
• Solubility: DMSO:50 mg/mL (79.51 mM);H2O:100 mg/mL (159.02 mM);Ethanol:17 mg/mL (27.03 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.18 mM)

Bioactivity

• Target IC50:
  DPP4:1 nM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Teneligliptin, FAP, MP513, MP-513, MP-513 (hydrobromide), MP 513, DPP-8, DPP-9, DPP, DPP4, Dipeptidyl peptidase-4, Dipeptidyl Peptidase

Compound Identifiers

PubChem CID

73173149