Telomerase-IN-8

SKU: orb3173076

Description

Telomerase-IN-8 is an orally active telomerase inhibitor with an IC50 value of 0.98 μM. It demonstrates substantial antiproliferative activity against various tumor cell lines, including PC3, Bcap-37, MGC-803, and HepG2. In xenograft mouse models with S180 sarcoma or HepG2 liver cancer, Telomerase-IN-8 exhibits notable antitumor effects. This compound is applicable for research in telomerase-targeted cancer therapy.

Research Area

Molecular Biology

Key Properties

• CAS Number: 1884341-01-8
• MW: 459.59
• Formula: C₂₈H₃₃N₃O₃
• SMILES: O=C1OC=2C=CC=CC2C=C1C3=NN(C(=O)CN(CCCC)CCCC)C(C=4C=CC=CC4)C3
• Target: Telomerase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Telomerase