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Catalog Number | orb1302375 |
---|---|
Category | Small Molecules |
Description | Telocinobufagin |
CAS Number | 472-26-4 |
Purity | 99.74% |
MW | 402.52 |
SMILES | O[C@@]12[C@]3([C@@]([C@]4(C)[C@](O)(CC3)C[C@@H](O)CC4)(CC[C@]1(C)[C@H](CC2)C=5C=CC(=O)OC5)[H])[H] |
Formula | C24H34O5 |
Biological Activity | 1. Telocinobufagin (Telobufotoxin) is the major endogenous digitalis-like factor. 2. Telocinobufagin significantly decreases the bacterial burdens in the spleen and prolongs the survival time of FIST-immunized mice challenged with live S. typhimurium. 3. Telocinobufagin has immunomodulatory activity, can enhance a Th1 immune response to control intracellular infections, could be developed as a novel immunotherapeutic agent to treat cancer and other immune-mediated diseases. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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