Tectoquinone

SKU: orb1297193

Description

Tectoquinone

Research Area

Infectious Disease & Virology, Molecular Biology

Key Properties

• CAS Number: 84-54-8
• MW: 222.24
• Purity: 97.05%
• Formula: C₁₅H₁₀O₂
• SMILES: O=C1C=2C(C(=O)C=3C1=CC=CC3)=CC=C(C)C2
• Target: Virus Protease,Others,SARS-CoV,DNA Alkylator/Crosslinker
• Solubility: DMSO:2.23 mg/mL (10.03 mM)

Bioactivity

• In Vitro:
  Mosquito larvicidal activities of methanolic extracts from different plant parts of red heartwood-type Cryptomeria japonica D. Don against the fourth-instar larvae of Aedes aegypti and Aedes albopictus were examined. Results of mosquito larvicidal tests demonstrated that the n-hexane fraction of C. japonica sapwood methanolic extract had an excellent inhibitory effect against the larvae of A. aegypti and A. albopictus and its LC50 values were 2.4 and 3.3 microg/ml, respectively, in 24h. Following the bioactivity-guided fractionation procedure, the active constituent isolated from C. japonica sapwood was characterized as Tectoquinone by spectroscopic analyses. The LC50 values of Tectoquinone against A. aegypti and A. albopictus in 24h were 3.3 and 5.4 microg/ml, respectively. In addition, comparisons of mosquito larvicidal activity of anthraquinone congeners demonstrated that anthraquinone skeleton with a methyl group at C-2 position, such as Tectoquinone, exhibited the strongest mosquito larvicidal activity.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Tectoquinone

Compound Identifiers

PubChem CID

6773