TEAD-IN-23

SKU: orb3174346

Description

TEAD-IN-23 (Compound 22) is a potent pan-TEAD inhibitor with an IC50 of 10 nM. It exhibits strong antiproliferative activity against NCI-H226 and MSTO-211H cell lines. In the MSTO-211H xenograft tumor model, TEAD-IN-23 causes complete tumor regression. This compound is suitable for research on mesothelioma and hepatocellular carcinoma.

Research Area

Stem Cell & Developmental Biology

Key Properties

• CAS Number: 3074990-47-6
• MW: 446.85
• Formula: C₂₃H₁₈ClF₃N₂O₂
• SMILES: FC(F)(F)C1=CC=C(OC2=CC(=CC(=C2)C)C3=CN(C=4C=CN=C(Cl)C34)CCO)C=C1
• Target: YAP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

YAP