TEAD-IN-13

SKU: orb2564599

Description

TEAD-IN-13 (64) is a potent, orally bioavailable TEAD autopalmitoylation inhibitor with an IC50 under 100 nM. Its 3.2-hour half-life in mice supports in vivo studies of Hippo pathway dysregulation in cancer research, enabling investigation of TEAD-dependent transcription in cellular and animal models.

Research Area

Stem Cell & Developmental Biology

Key Properties

• CAS Number: 3034813-74-3
• MW: 461.43
• Formula: C₂₃H₂₂F₃N₃O₄
• SMILES: C(=O)(C1C(C1)C=2C=3C(C=C(OC4=CC=C(C(F)(F)F)C=C4)C2)=CN(C)N3)N5C[C@H](O)[C@@H](O)C5
• Target: YAP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171714308