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TEAD-IN-11

SKU: orb2564709

Description

TEAD-IN-11 (compound 38) is a potent and selective covalent inhibitor of TEAD1, TEAD2, and TEAD3 isoforms, with IC50 values in the low nanomolar range. This tool compound is valuable for investigating Hippo pathway signaling in cancer research, supporting both in vitro and in vivo studies of TEAD-dependent transcription and oncogenesis.

Research Area

Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number3032196-88-3
MW293.28
FormulaC16H14F3NO
SMILESO=C(C=C)N1CCC(C#CC2=CC=C(C=C2)C(F)(F)F)C1
TargetYAP

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information