TEAD-IN-10

SKU: orb2565189

Description

TEAD-IN-10 (compound 15) is a potent and selective covalent inhibitor of TEAD1, TEAD2, and TEAD3, with single-digit to sub-100 nM IC50 values. It is a valuable chemical probe for investigating Hippo pathway signaling in cancer research, applicable in both in vitro and in vivo experimental models.

Research Area

Stem Cell & Developmental Biology

Key Properties

• CAS Number: 3032196-65-6
• MW: 281.27
• Formula: C₁₅H₁₄F₃NO
• SMILES: C(=C/C1=CC=C(C(F)(F)F)C=C1)\C2CN(C(C=C)=O)C2
• Target: YAP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171092856