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TDO-IN-2

SKU: orb3028007

Description

TDO-IN-2 is an orally active TDO inhibitor with an IC50 of 1.25 μM. It exhibits antitumor activity in a Hepa1-6 liver cancer allograft mouse model. Additionally, TDO-IN-2 works synergistically with PD-1/PD-L1 inhibitor BMS-202, making it useful for studying tumor immune tolerance.

Research Area

Metabolism Research

Images & Validation

Key Properties

FormulaC20H15N3O3
TargetIndoleamine 2,3-Dioxygenase (IDO),IDO

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information