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TDI-014925

SKU: orb3173206

Description

TDI-014925 (Compound 58) is an inhibitor of the SARS-CoV-2 methyltransferase non-structural protein 14 (NSP14), with an IC50 value of 0.2 nM. It exhibits antiviral activity and demonstrates significant microsomal stability, but does not have CYP inhibition activity. TDI-014925 is applicable for COVID-19 research.

Images & Validation

Key Properties

CAS Number3052313-53-5
MW485.54
FormulaC22H24FN7O3S
SMILESO=C(NCC1=C(F)C=CC=2C=NN(C21)C)C3=CC(=C(N3C)C)S(=O)(=O)N4CC5=CNN=C5CC4
TargetSARS-CoV

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information