TD114-2

SKU: orb2564366

Description

TD114-2 (compound 29) is a potent, selective GSK-3β inhibitor (IC50 = 48 nM) with selectivity conferred by a key interaction with ARG141. It is a valuable research tool for studying GSK-3β's role in diabetes and neurodegenerative disease models, applicable in both in vitro and in vivo experimental settings.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 436866-52-3
• MW: 529.58
• Formula: C₃₀H₃₁N₃O₆
• SMILES: O=C1NC(=O)C=2C3=CN(C=4C=CC=CC34)CCOCCOCCOCCOCCN5C=C(C=6C=CC=CC65)C12
• Target: GSK-3

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

10208648