TCIP 1

SKU: orb1980179

Description

TCIP 1 is a covalent transcriptional/epigenetic probe that targets BCL6 and BRD4, forming a ternary complex to reactivate apoptosis and suppress MYC. It demonstrates potent anti-proliferative effects in DLBCL models, supporting its use in oncology research for studying transcriptional regulation and targeted protein degradation both in vitro and in vivo.

Research Area

Epigenetics & Chromatin

Key Properties

• MW: 1026.04
• Formula: C₅₀H₅₈Cl₂N₁₂O₆S
• SMILES: CNC(COC1=CC2=C(C(OC)=CC(NC3=NC(N4CCC(C(NCCCCCCCNC(C[C@@H]5N=C(C6=CC=C(Cl)C=C6)C7=C(SC(C)=C7C)N8C(C)=NN=C58)=O)=O)CC4)=NC=C3)=C2)N(C)C1=O)=O
• Target: Epigenetic Reader Domain

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171361084