TC-DAPK 6

SKU: orb1706572

Description

TC-DAPK 6 is a potent, ATP-competitive small molecule inhibitor targeting Death-associated protein kinase, exhibiting IC50 values of 69 nM for DAPK1 and 225 nM for DAPK3. This compound is a valuable research tool for investigating DAPK signaling in cellular models of apoptosis, autophagy, and neurological diseases in vitro.

Research Area

Cell Biology

Key Properties

• CAS Number: 315694-89-4
• MW: 276.29
• Purity: 98.73%
• Formula: C₁₇H₁₂N₂O₂
• SMILES: C(=C1C(=O)OC(C=CC2=CC=CC=C2)=N1)C=3C=CC=NC3
• Target: DAPK
• Solubility: DMSO:16.8 mg/mL (60.81 mM)

Bioactivity

• Target IC50:
  DAPK1:69 nM|DAPK3:225 nM
• In Vitro:
  TC-DAPK 6 inhibits p70S6K with IC50s of 1 μM-10 μM.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DAPK3, DAPK, DAPK1, TCDAPK 6, TC-DAPK 6, TC DAPK 6

Compound Identifiers

PubChem CID

3275571