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TC-2153 HCl
Catalog Number: orb1738662
| Catalog Number | orb1738662 |
|---|---|
| Category | Small Molecules |
| Description | TC-2153 HCl |
| CAS Number | 1381769-23-8 |
| Purity | 0.98 |
| MW | 355.8692 |
| SMILES | Cl.FC(F)(F)C1=CC=2SSSSSC2C(N)=C1 |
| Formula | C7H5ClF3NS5 |
| Biological Activity | TC-2153 is a potent inhibitor of STEP (STriatal-Enriched protein tyrosine Phosphatase) that forms a reversible covalent bond with the catalytic cysteine in STEP. TC-2153 increases tyrosine phosphorylation of STEP substrates ERK1/2, Pyk2, and GluN2B in cell cultures. TC-2153 improves cognitive function in transgenic AD mice. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
