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TBPB

SKU: orb1307513

Description

TBPB is a selective positive allosteric modulator of the M1 muscarinic acetylcholine receptor. It is a valuable research tool for studying M1 receptor function in vitro and has been used in animal models to investigate its potential in cognitive disorders.

Research Area

Neuroscience

Images & Validation

Key Properties

CAS Number634616-95-8
MW404.55
Purity99.97% (May vary between batches)
FormulaC25H32N4O
SMILESCc1ccccc1CN1CCC(CC1)N1CCC(CC1)n1c2ccccc2[nH]c1=O
TargetAChR,Beta Amyloid
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.47 mM);DMSO:4.05 mg/mL (10.01 mM)

Bioactivity

Target IC50
M1 mAChR (allosteric):289 nM(ec50)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

TBPB, M1 mAChR, mAChR, inhibit, Muscarinic acetylcholine receptor, Inhibitor

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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Protocol Information

TBPB (orb1307513)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

5 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 110.00
10 mg
$ 110.00
25 mg
$ 160.00
50 mg
$ 240.00
100 mg
$ 410.00
200 mg
$ 590.00
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