TB-9

SKU: orb2814319

Description

TB-9, a Tasiamide B derivative, is a potent small molecule inhibitor of Cathepsin D (IC50=0.0783 nM), Cathepsin E (IC50=0.724 nM), and BACE1 (IC50=54.2 nM). This compound is a valuable research tool for studying Alzheimer's disease pathology and aspartic protease function in both cellular and biochemical assays.

Research Area

Neuroscience, Protein Biochemistry

Key Properties

• CAS Number: 1415033-91-8
• MW: 1041.24
• Formula: C₅₅H₇₆N₈O₁₂
• SMILES: C([C@@H](CC1=CC=CC=C1)N(C([C@@H](NC([C@@H](NC(C[C@@H]([C@H](CC2=CC=CC=C2)NC([C@@H](N(C([C@@H](NC(OCC3=CC=CC=C3)=O)C(C)C)=O)C)CCC(N)=O)=O)O)=O)CC(C)C)=O)C)=O)C)(=O)N4[C@H](C(OC)=O)CCC4
• Target: Cysteine Protease,Beta-Secretase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

71453880