TAXUSIN

SKU: orb1680055

Description

TAXUSIN

Key Properties

• CAS Number: 19605-80-2
• MW: 504.61
• Purity: 99.91% (May vary between batches)
• Formula: C₂₈H₄₀O₈
• SMILES: C[C@]12[C@@H](OC(C)=O)[C@H](OC(C)=O)C=3C(C)(C)[C@](C[C@@]1(C(=C)[C@@H](OC(C)=O)CC2)[H])(C[C@H](OC(C)=O)C3C)[H]
• Target: Others
• Solubility: DMSO:6.25 mg/mL (12.39 mM)

Bioactivity

• Target IC50:
  NO:22.1 μM
• In Vivo:
  METHODS: Taxusin was administered to mice at 30 mg/kg by intraperitoneal injection to treat the painful effect of abdominal contraction caused by p-benzoquinone. RESULTS Taxusin exhibited significant analgesic effects on abdominal contractions induced by p-benzoquinone.
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• In Vitro:
  METHODS: Taxusin and verapamil (0.1/1/10μg/mL) were used to determine the accumulation of vincristine (VCR) in multi-drug-resistant human ovarian cancer 2780AD cells. RESULTS Taxusin's activity against VCR accumulation in multidrug-resistant tumor cells was approximately 1.5 times that of microverapamil.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

TAXUSIN

Compound Identifiers

PubChem CID

167825