Tauroursodeoxycholate dihydrate

SKU: orb1706575

Description

Tauroursodeoxycholate dihydrate (TUDCA) is a water-soluble bile acid that acts as a chemical chaperone to inhibit endoplasmic reticulum stress and apoptosis. It is widely used in research on neurodegenerative, metabolic, and liver diseases, demonstrating protective effects in both cellular and animal models by stabilizing mitochondria and reducing caspase activation.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 117609-50-4
• MW: 535.73
• Purity: 99.82% (May vary between batches)
• Formula: C₂₆H₄₉NO₈S
• SMILES: C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(NCCS(=O)(O)=O)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@](C[C@@H](CC4)O)([H])C[C@@H]3O)C.O.O
• Target: JNK,IRE1,Akt,ROS,ERK,NF-κB,Apoptosis,Endogenous Metabolite,Caspase
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.73 mM);DMSO:60 mg/mL (112 mM)

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Caspase-3, Caspase-12, ERK, TUDCA, TUDCA dihydrate, Taurolite, Taurolite dihydrate, Tauroursodeoxycholate, Tauroursodeoxycholic acid dihydrate, Tauroursodeoxycholate dihydrate, UR906 Dihydrate, UR-906 Dihydrate, UR 906 dihydrate, UR 906, UR906, UR-906

Compound Identifiers

PubChem CID

71306862