Tat-NR2B9c

SKU: orb1708392

Description

Tat-NR2B9c (NA-1) is a neuroprotective PSD-95 inhibitor that disrupts the PSD-95/NMDA receptor interaction. This action inhibits downstream NADPH oxidase activation and superoxide production, offering a mechanism to reduce neuronal injury in models of stroke and epilepsy, as evidenced in both in vitro and in vivo studies.

Research Area

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• Target: iGluR,NO Synthase
• CAS Number: 500992-11-0
• MW: 2518.88
• Purity: 99.71% (May vary between batches)
• Formula: C₁₀₅H₁₈₈N₄₂O₃₀
• SMILES: CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(O)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NOSynthase, NO synthase, NO Synthase, NA 1, NA1, NA-1, iGluR, TatNR2B9c, Tat-NR2B9c, Tat-NR-2B9c, Tat-NR2Bct, Tat NR2B9c, PSD-95d1, PSD-95d2

Compound Identifiers

PubChem CID

44568939