TAT-MKK3b

SKU: orb2813697

Description

TAT-MKK3b is a cell-permeable peptide inhibitor of p38 MAPK phosphorylation. Its renal-targeted action, demonstrated in experimental models, reduces oxidative stress and ferroptosis, showing potential for ameliorating both acute kidney injury and its progression to chronic kidney disease in research settings.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• Target: p38 MAPK,Ferroptosis,Reactive Oxygen Species
• CAS Number: 928163-65-9
• MW: 3055.64
• Formula: C₁₂₉H₂₄₀N₅₆O₃₀
• SMILES: [C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC1=CC=C(O)C=C1)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](CC)C)C(O)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)CC(O)=O)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCCN)=O)CO)=O)CCCCN)=O)=O)CCCCN)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

176055052