TAT-MEK1

SKU: orb2563708

Description

TAT-MEK1 is a cell-permeable inhibitor of ERK2, consisting of the HIV-1 TAT peptide fused to the N-terminus of MEK1. It exhibits an in vitro IC50 of 29 μM against ERK2 and is used in research to study MAPK/ERK signaling pathways in cellular and experimental models.

Research Area

Signal Transduction

Key Properties

• Target: ERK
• CAS Number: 566872-16-0
• MW: 3146.77
• Formula: C₁₃₆H₂₄₁N₅₃O₃₁S
• SMILES: C([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]1N(C([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC2=CC=C(O)C=C2)NC(CN)=O)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)CCSC)=O)CCC1)CCCCN)=O)CCCCN)=O)CCCCN)(=O)N3[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N5[C@H](C(N)=O)CCC5)CC(N)=O)=O)CC(C)C)=O)CCC(N)=O)=O)[C@H](CC)C)=O)CCC4)[C@@H](C)O)=O)CCC3

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172653489