TAT-JIP

SKU: orb1943728

Description

TAT-JIP is a cell-permeable inhibitor that effectively blocks the phosphorylation of endogenous c-Jun, a key step in its activation pathway induced by stimuli such as PHA-PMA. This makes it a valuable tool for studying JNK signaling in cellular models of inflammation, proliferation, and apoptosis both in vitro and in vivo.

Research Area

Cancer Biology, Signal Transduction

Key Properties

• Target: JNK
• CAS Number: 1623722-15-5
• MW: 2883.42
• Formula: C₁₂₅H₂₂₀N₅₂O₂₇
• SMILES: C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC1=CC=C(O)C=C1)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N)=O)=O)CC(C)C)=O)CC(N)=O)=O)CC(C)C)=O)[C@@H](C)O)=O)[C@@H](C)O)=O)CCC3)CCCNC(=N)N)=O)CCCCN)=O)CCC2

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171361105