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Tasquinimod

SKU: orb1225504

Description

An orally active antiangiogenic agent with anti-prostate cancer activity, an allosteric modulator of HDAC4 with Kd of 10-30 nM; inhibits colocalization of N-CoR/HDAC3, thereby inhibiting deacetylation of histones and HDAC4 client transcription factors, such as HIF-1α.Prostate cancer Phase 3 Clinical.

Images & Validation

Key Properties

CAS Number254964-60-8
MW406.3552
Purity>98% (HPLC)
FormulaC20H17F3N2O4
SMILESO=C(C1=C(O)C2=C(N(C)C1=O)C=CC=C2OC)N(C)C3=CC=C(C(F)(F)F)C=C3
TargetHDAC
SolubilityDMSO: ≥ 42 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

ABR-215050 | ABR215050 | ABR 215050

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Quality Guarantee

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Tasquinimod (orb1225504)

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Available Sizes

Select a size below

2 mg
$ 110.00
5 mg
$ 140.00
10 mg
$ 190.00
25 mg
$ 300.00
50 mg
$ 430.00
100 mg
$ 640.00
500 mg
$ 1,380.00