Tasquinimod

SKU: orb1225504

Description

An orally active antiangiogenic agent with anti-prostate cancer activity, an allosteric modulator of HDAC4 with Kd of 10-30 nM; inhibits colocalization of N-CoR/HDAC3, thereby inhibiting deacetylation of histones and HDAC4 client transcription factors, such as HIF-1α.Prostate cancer Phase 3 Clinical.

Key Properties

• CAS Number: 254964-60-8
• MW: 406.3552
• Purity: >98% (HPLC)
• Formula: C₂₀H₁₇F₃N₂O₄
• SMILES: O=C(C1=C(O)C2=C(N(C)C1=O)C=CC=C2OC)N(C)C3=CC=C(C(F)(F)F)C=C3
• Target: HDAC
• Solubility: DMSO: ≥ 42 mg/mL

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ABR-215050 | ABR215050 | ABR 215050

Quick Database Links

Gene Symbol

HDAC