TAS2940 fumarate

SKU: orb2646030

Description

TAS2940 fumarate is an orally bioavailable, brain-penetrant irreversible pan-ERBB inhibitor with potent activity against wild-type HER2 (IC50 5.6 nM) and its mutants. It is a research tool for studying HER2/EGFR-driven tumors in both cellular assays and in vivo models.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 2758034-98-7
• MW: 598.65
• Formula: C₃₂H₃₄N₆O₆
• SMILES: C(=C/C(O)=O)\C(O)=O.C(#CC1CC1)C=2N(C=3C(C2C(N[C@H](C)C4=CC=CC=C4)=O)=C(N)N=CN3)[C@H]5CN(C(C=C)=O)[C@@H](C)C5
• Target: EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171904656