TAS05567

SKU: orb1706576

Description

TAS05567 is a potent and highly selective ATP-competitive inhibitor of Syk with an IC50 of 0.37 nM. It demonstrates selectivity, showing significant activity against only four other kinases (FLT3, JAK2, KDR, RET) in a broad panel. This inhibitor is a valuable tool for investigating Syk-dependent signaling pathways in both in vitro and in vivo immunological and oncological research contexts.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1429038-15-2
• MW: 439.51
• Formula: C₂₁H₂₉N₉O₂
• SMILES: CC=1C=2C(=CN(C(C)(C)C)N2)C=C(NC=3C(C(N)=O)=NN=C(N[C@H]4[C@@H](N)COCC4)N3)C1
• Target: c-RET,Syk,FLT,JAK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

71543230